This study was carried out to determine the effects of Moringa oleifera seeds on the microbial and physiological parameters of industrial and kitchen effluents. Different concentrations of the moringa seeds (1%, 2%, 4% and 8%) were prepared and used to treat known volumes of domestic and kitchen effluents using alum (1%) as control for a 4 day treatment period. Phytochemical screening, coagulation and microbiological studies were carried out using standard methods. The results revealed the presence of several phytochemicals including flavonoids, alkaloids, cardiac glycosides, saponins, reducing sugars, terpenoids and carotenoid in both the ethanol and aqueous extracts of the moringa seeds. Coagulation studies revealed that the pH of the industrial effluent treated with 1% alum (control) and 1% moringa increased from day 1 (pH 3.75) to day 4 (pH 4.0). Conductivity values showed that the industrial effluent treated with 8% moringa had the highest conductivity value on day 1(2470/m) while 1% moringa treated group had the lowest conductivity value on day 4 (1000 ?/m). microbial studies revealed that the lowest values for heterotrophic count (83 x 102), coliform count on MAC agar (124 x 102) and coliform count on Eosin methylene blue (EMB) agar (130 x 102) for the industrial effluent. Industrial effluent treated with 1% moringa had the lowest Most probable number (MON) value of 7 on day 4. The results showed that moringa oliefera seeds have good coagulation abilities and can be used in water treatment processes. However, further research into optimum parameters required for efficient treatment of effluents should be encouraged