This research work is focused on the design and implementation of patient management system using Central Hospital, Ughelli as a case study. This system is used to manage patient information and its administration. This was with a view to eliminate the problem of inappropriate data Keeping, inaccurate reports, time wastage in storing, processing and retrieving information encountered by the traditional hospital system in order to improve the overall efficiency of the organization. The tools used to implement the system are ASP.Net, Cascading Style Sheets (CSS), VB.Net, and Microsoft Access. The Proposed system was tested using the information collected from Central Hospital, Ughelli Delta State, Nigeria and compared with the existing traditional hospital system. The design provides excellent patient services and improved information infrastructure. The research methodology used for the system’s design is System Development Life Cycle.